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Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody

Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody

€652.00

Excl. VAT

Item no.	BOS-M09548
Manufacturer	Boster
Amount	100ug
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Hematology Myeloma Cell Biology Cell Status Necrosis Apoptosis Immunohistochemistry Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	IF, IHC
Clone	NK/804
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgM Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1;2.4.1.135;Beta-1,3-glucuronyltransferase 1;Glucuronosyltransferase P;GlcAT-P;UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase;GlcUAT-P;B3GAT1;GLCATP;
Available
Manufacturers Product Category	Primary Antibodies, Monoclonal Antibodies
Manufacturers Research Category	Cell Type Markers, Immunology, NK Cells
Short Description	Boster Bio Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody (Catalog # M09548). Tested in IF, IHC applications. This antibody reacts with Human.
Description	Boster Bio Anti-CD57 / B3GAT1 (Natural Killer Cell Marker) Monoclonal Antibody (Catalog # M09548). Tested in IF, IHC applications. This antibody reacts with Human.
Background	Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
Gene Name	B3GAT1
Clonality	Monoclonal
Concentration	Purified antibody with BSA and azide at 200ug/ml
Contents	Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Application Details	Immunofluorescence (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Immunogen	Membrane antigen from HSB-2 cells
Purification	200ug/ml of antibody purified from Bioreactor Concentrate.
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Gene Full Name	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1
Molecular Weight	38256 MW
Protein Function	Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity)..
Subcellular Localization	Cell surface
Tissue Specificity	Mainly expressed in the brain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

Listprice: €652.00

Price: €652.00

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Delivery expected until 9/4/2025

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