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IL-8 (V68) polyclonal antibody

IL-8 (V68) polyclonal antibody

€262.00

Excl. VAT

Item no.	BS3479-50
Manufacturer	Bioworld Technology, Inc
Amount	50ul
Category	Neuroscience Neuroinflammation Metabolism Diabetes Neural Signaling Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Interleukin-8, IL-8, C-X-C motif chemokine 8, Emoctakin, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil chemotactic factor, MDNCF, Monocyte-derived neutrophil-activating peptide, MONAP, Neutrophil-activating protein 1, NAP-1 Protein
Similar products	IL-8
Available
Swiss-Prot	P10145
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	IL-8 has been shown to function as a potent neutrophil chemostatic and activating peptide and is an important mediator of inflammatory diseases. Two distinct human IL-8 receptors, designated IL-8RA and IL-8RB, have been characterized. Both are expressed at a high level on neutrophils, and to a lesser extent on monocytes and myeloid cell lines. In addition, the IL-8RA subunit is expressed in T cells such as the Jurkat cell line. Both IL-8Rs are members of the seven-transmembrane domain rhodopsin superfamily of receptors and as such, couple G proteins for signal transduction. The two receptors share 77% amino acid identity.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	IL-8 (V68) pAb detects endogenous levels of IL-8 protein.
WB	Western blot (WB) analysis of IL-8 (V68) pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
IHC	Immunohistochemistry (IHC) analyzes of IL-8 (V68) pAb in paraffin-embedded human lung carcinoma tissue at 1:100.
BiowMW	ca. 38 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Interleukin-8, IL-8, C-X-C motif chemokine 8, Emoctakin, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil chemotactic factor, MDNCF, Monocyte-derived neutrophil-activating peptide, MONAP, Neutrophil-activating protein 1, NAP-1 Protein 3-10C, T-cell chemotactic factor, CXCL8, IL8
Immunogen	Synthetic peptide, corresponding to amino acids 21-70 of Human IL-8.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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