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Anti-Mouse CD127 (IL-7Ra) FITC Size 25 ug

Anti-Mouse CD127 (IL-7Ra) FITC Size 25 ug

€84.00

Excl. VAT

Item no.	19212-50-25
Manufacturer	BioGems
Amount	25 ug
Category	Oncology Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Primary Antibodies By Organ Bone Cancer
Type	Antibody
Format	FITC
Applications	FC
Clone	A7R34
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a kappa
Conjugate/Tag	FITC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The A7R34 monoclonal antibody specifically reacts with the mouse CD127, the α subunit of the IL-7 receptor, expressed by immature B lymphocytes in the bone marrow, CD4-/CD8-, CD4+, and CD8+ thymocytes, and by mature T lymphocytes at low levels. Mature T cells express CD117 at low levels in the periphery. The A7R34 antibody prevents the interaction between IL-7 and its receptor and the binding of mAb SB/199, which also recognizes mouse CD127.
Research Interest	Adaptive Immunity
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References	Sudo, T., Nishikawa, S. A. T. O. M. I., Ohno, N. O. R. I. K. O., Akiyama, N. A. O. K. O., Tamakoshi, M. A. S. A. T. A. D. A., & Yoshida, H. I. S. A. H. I. R. O. (1993). Expression and function of the interleukin 7 receptor in murine lymphocytes. Proceedings of the National Academy of Sciences, 90(19), 9125-9129. Hashi, H., Yoshida, H., Honda, K., Fraser, S., Kubo, H., Awane, M., ... & Nishikawa, S. I. (2001). Compartmentalization of Peyer's patch anlagen before lymphocyte entry. The Journal of Immunology, 166(6), 3702-3709. Okuno, Y., Iwasaki, H., Huettner, C. S., Radomska, H. S., Gonzalez, D. A., Tenen, D. G., & Akashi, K. (2002). Differential regulation of the human and murine CD34 genes in hematopoietic stem cells. Proceedings of the National Academy of Sciences, 99(9), 6246-6251.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 ug

Listprice: €84.00

Price: €84.00

available

Delivery expected until 8/28/2025

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