Comparison

Anti-Mouse CD30 SAFIRE Purified 100 ug

€217.00
Excl. VAT
Item no. 02412-25-100
Manufacturer BioGems
Amount 100 ug
Category
Type Antibody
Format SAFIRE Purified
Applications FC
Clone mCD30.1
Specific against Mouse (Murine, Mus musculus)
Host Hamster
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Description
The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on activated T, B, NK, and monocyte cells. Its expression on activated T lymphocytes is regulated by cytokines and CD28. The ligand for CD30 is CD153. It has been suggested that the molecule plays a role in the protection against autoimmunity and the regulation of Th1 and Th2 cytokine secretion.
Research Interest
Apoptosis
Preperation
The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Formulation
Phosphate-buffered aqueous solution, ph7.2.
References

Siegmund, T., Armitage, N., Wicker, L. S., Peterson, L. B., Todd, J. A., & Lyons, P. A. (2000). Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9. 2. Diabetes, 49(9), 1612-1616.

Falini, B., Pileri, S., Pizzolo, G., Dürkop, H., Flenghi, L., Stirpe, F., ... & Stein, H. (1995). CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy. BLOOD-NEW YORK-, 85, 1-1.

Heath, W. R., Kurts, C., Caminschi, I., Carbone, F. R., & Miller, J. F. (1999). CD 30 prevents T-cell responses to non-lymphoid tissues. Immunological reviews, 169(1), 23-29.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
Listprice: €217.00
Price: €217.00
available

Delivery expected until 9/11/2025 

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