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WRW4

€56.00
Excl. VAT
Item no. BAC-4095537.0001
Manufacturer Bachem
Amount 1mg
Category
Type Reagents
Specific against other
ECLASS 10.1 42051003
ECLASS 11.0 42051003
UNSPSC 12000000
Alias 878557-55-2
Available
Description
Antagonist of formyl peptide receptor-like 1 (FPRL1) signalling. WRW4 inhibits WKYMVm binding to FPRL1 (IC5o 0.23 mM) as well as the intracellular calcium release induced by WKYMVm, MMK-1, amyloid beta42, and F peptide. The tryptophan-rich peptide also inhibits FPRL1-mediated signalling in human neutrophils and blocks chemotactic migration and superoxide generation by Abeta42. WRW4 inhibited the activation of FPRL2 by F2L (H-6294), an FPRL2-selective endogenous agonist, resulting in the complete inhibition of intracellular calcium increase and chemotactic migration.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
Listprice: €56.00
Price: €56.00
available

Delivery expected until 9/4/2025 

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