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VEGF Protein (OPPA00525)

VEGF Protein (OPPA00525)

Item no.	OPPA00525
Manufacturer	AVIVA Systems Biology
Amount	2ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Adenocarcinoma By Organ Bladder Cancer
Type	Proteins
Format	The protein was lyophilized from a Phosphate- Buffered Saline, pH 7.4. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against	other
Host	Hamster
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609, VEGF Human, CHO, Vascular Endothelial Growth Factor Human Recombinant, CHO
Similar products	VEGF CHO
Available
Description	Vascular Endothelial Growth Factor Human Recombinant produced in CHO cells is a double, glycosylated, polypeptide chain containing 165 amino acids and migrates as 44 kDa in SDS-PAGE under non-reducing conditions.
Gene symbol	VEGF
Protein name	Vascular endothelial growth factor A
Molecular weight	44 kDa (SDS-PAGE)
Product format	Lyophilized. from PBS, pH 7.4 Physical Appearance: Sterile filtered white powder
Gene id	7422
Reconstitution and storage	It is recommended to reconstitute the lyophilized Vascular Endothelial Growth Factor Human in sterile 18MΩ -cm H₂O no less than 100 μ g/mL, which can then be further diluted to other aqueous solutions. Lyophilized Vascular Endothelial Growth Factor Human, although stable at room temperature for 3 weeks, should be stored desiccated below 18° C. Upon reconstitution, VEGF Human Recombinant should be stored at 4° C between 2-7 days and for future use below -18° C. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze/thaw cycles.
Description of target	Vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/ macrophagemigration, neurons, cancer cells, kidney epithelial cells ). VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesisand cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.
Purification	The VEGF is purified by proprietary chromatographic techniques.
Biological activity	The protein was tested in HUVEC cells, the ED₅₀ for this effect was found to be 2-6 ng/ml.
Warning	Products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Purity	Greater than 97.0% as determined by SDS-PAGE.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2ug

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Delivery expected until 9/11/2025

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