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MYC Peptide (AAP38157)

MYC Peptide (AAP38157)

€151.00

Excl. VAT

Item no.	AAP38157
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Western Blot Peptides By Organ Bladder Cancer Neurodegeneration Markers
Type	Peptides
Format	Lyophilized powder
Applications	WB
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	c-Myc
Similar products	MYC
Available
Description	This is a synthetic peptide designed for use in combination with anti-MYC antibody (Catalog #: ARP38157_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	MYC
Protein size	60
Molecular weight	7kDa
Product format	Lyophilized powder
Gene id	4609
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins	E2F1, E2F4, E2F5, CHUK, ESR1, FUBP1, NCOA3, ORC2L, POLR2A, XRCC5, BRCA1, CDK4, CDKN1A, CDKN1A, CDKN1A, CDKN2A, CSNK2A1, DDB2, DNMT3A, FBXW7, FBXW7, KAT2A, MAPK3, MAX, MIR17HG, MLH1, MYCBP2, NCL, NFYB, NFYC, NMI, NPM1, PARP10, PMAIP1, PML, RIBIN, RRM2B, SP1, SP1, TAF1A, TAF1B, TAF1C, TBP, TRRAP, ACTL6A, BCL2, BIN1, BRCA1, CCNT1, CDC6, CDK1, CDKN2A, CEBPA, CEBPB, CREBBP, CSNK2A1, CSNK2A2, DNMT3A, ELF3, EP300, FBXW7, GSK3B, GTF2F1, GTF2I, HSP90AA1, KAT2A, KAT5, MAP2K1, MAPK3, MAPK7, MAPK8, MAX, MINA, MLH1, MXD1, MXI1, MYCBP, MYCBP2, NFYB, NFYC, NMI, PARP10, PFDN5, PML, PRDX1, RAF1, RAGE, RB1, RBL1, RELA, SKP2, SMAD2, SMAD3, SMARCB1, SNIP1, SP1, SPAG9, SUPT3H, TAF1B, TBP, TFAP2B, TIAM1, TP73, TRRAP, TUBA1A, TUBA1B, TUBA3C, TUBA4A, TUBA8, UBB, YY1, ZBTB17, ACTB, ACTL6A, ARHGEF2, BCL2, BRCA1, BRD7, CCNT1, CD6, CDC6, CDK9, CEBPA, CEBPB, DDX24, DNMT3A, EFTUD2, EP400, EXOC4, Eif4e, FANCI, FBXW7, GCN1L1, GEMIN4, GTF2B, GTF2F1, GTF2I, GTF3C3, HEATR1, HNRNPC, HSP90AA1, KAT2A, KAT2B, KAT5, KIAA1967, MAPK1, MAPK3, MAPK8, MAX, MCM7, MED12, MED14, METTL13, MKLN1, MLH1, MSH2, MSH6, MYBBP1A, MYCBP, MYCBP2, MYO1B, NFYB, NFYC, NMI, NUP205, NUP93, PDS5A, PFDN5, PIAS2, POLE, POLR2A, PRPF8, RAF1, RB1, RBL1, RELA, RUVBL1, RUVBL2, SAP130, SMAD2, SMAD3, SMARCA4, SMARCB1, SNRNP200, SP1, SUPT3H, TADA2A, TADA3, TAF10, TAF12, TAF5, TAF5L, TAF6L, TAF9, TBP, TFAP2A, TIAM1, TP73, TRRAP, UBB, YY1, ZBTB17
Description of target	MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this MYC gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

Listprice: €151.00

Price: €151.00

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Delivery expected until 9/11/2025

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