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MITF Antibody - middle region (ARP31212_P050)

MITF Antibody - middle region (ARP31212_P050)

Item no.	ARP31212_P050
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Neural Development Neural Adhesion Molecules Antibodies By Cell Type Melanoma Western Blot Primary Antibodies By Organ Bladder Cancer Glial Cell Markers Neuronal Cell Markers Macrophage Markers
Type	Antibody Polyclonal
Format	Lyophilized powder
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CMM8, MI, WS2, WS2A, bHLHe32
Available
Gene symbol	MITF
Protein name	Microphthalmia-associated transcription factor
Protein size	357
Molecular weight	39kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	4286
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	EBP. STUB1. HK3. EPAS1. LEF1. APP. HINT1. ELAVL1. CDK2. SUMO2. PSMD14. MARK3. PIAS3. PIAS2. PIAS1. SUMO1. UBE2I. PAX3. OTX2. PAX6. PATZ1. GSK3B. TFEC. EP300. RPS6KA1. TFEB. MAPK14. TFE3. MAPK1. SPI1. FOS. CTNNB1. CDKN1A. RB1.
Description of target	MITF is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the middle region of Human MITF
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 7/31/2025

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