SARS-CoV-2 (COVID-19) NSP6 Antibody

Infectious Disease, COVID-19

Anti-SARS-CoV-2 (COVID-19) NSP6 antibody (9177) was raised against a peptide corresponding to 18 amino acids in the center of SARS-CoV-2 (COVID-19) NSP6 protein.

The immunogen is located in between 230-280 amino acids of the SARS-CoV-2 (COVID-19) NSP6 protein.

SARS-CoV-2 (COVID-19) NSP6 Antibody is affinity chromatography purified via peptide column.

IgG

SARS-CoV-2 (COVID-19) NSP6 Antibody is supplied in PBS containing 0.02% sodium azide.

SARS-CoV-2 (COVID-19) NSP6 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

YP_009742613.1

43740578

ORF1ab

Severe acute respiratory syndrome coronavirus 2

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP6 plays a role in the initial induction of autophagosomes from host reticulum endoplasmic. Later, it limits the expansion of these phagosomes that are no longer able to deliver viral components to lysosomes (3, 4).

Hui et al. Int J Infect Dis. 2020; 91:264-266.

Cottam et. al. Autophagy 2014; 10:1426-1441