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Estrogen Receptor-alpha (phospho Tyr537) Antibody

Estrogen Receptor-alpha (phospho Tyr537) Antibody

€503.00

Excl. VAT

Item no.	PRS-79-786-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ER, ESR, ESR1, ESTR, NR3A1
Available
Shipping	blue ice or RT
By Research Area	Phospho-Specific
Immunogen	Estrogen Receptor-alpha (phospho Tyr537) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 537 (P-L-Y (p)-D-L) derived from Human Estrogen Receptor-alpha.
Applications	Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity	The antibody detects endogenous levels of ER-alpha only when phosphorylated at tyrosine 537.
Predicted Molecular Weight	66 kDa
Purification	Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1 mg/mL
Storage Conditions	Store antibody at -20˚ C for up to one year.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	Phospho-Specific
Ncbi Official Symbol	ESR1
Accession #	NP_000116.2
Protein Gi #	62821794
Ncbi Gene Id #	2099
Ncbi Official Symbol	ESR1
Ncbi Official Full Name	estrogen receptor 1
Ncbi Organism	Homo sapiens
Swissprot #	P03372
Background	Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Background References 1	Sehime Temel, Endocrinology, Oct 2002; 143: 3974.
Background References 2	Xin-Tian Zhang, AACR Meeting Abstracts, Apr 2005; 2005: 302.
Background References 3	Suwit J. Somponpun, Am J Physiol Regulatory Integrative Comp Physiol, Sep 2004; 287: R661 - R669.
Background References 4	Marcello Maggiolini, Cancer Res., Oct 1999;
1st Image Caption	Western blot analysis of extracts from K562 cells (Lane 2), using Estrogen Receptor-alpha (Phospho-Tyr537) Antibody. The lane on the left is treated with antigen-specific peptide.
2nd Image Caption	Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Estrogen Receptor-alpha (Phospho-Tyr537) antibody (left) or the same antibody preincubated with blocking peptide (right).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

Listprice: €503.00

Price: €503.00

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Delivery expected until 10/2/2025

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