TAF9 Antibody

Homeostasis

TAF9 antibody was raised against a 17 amino acid peptide near the center of human TAF9.

The immunogen is located within amino acids 110 - 160 of TAF9.

TAF9 antibody is human, mouse and rat reactive. Multiple isoforms of TAF9 are known to exist. TAF9 is predicted to not cross-react with other TAF family members.

Predicted: 29 kDa

Observed: 28 kDa

Polyclonal

Unconjugated

1 mg/mL

Cat. No. 7719P – TAF9 Peptide

None

NP_003178

6880

TAF9

homo sapiens

Initiation of transcription by RNA polymerase II is coordinated by the transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and the TBP-associated factors (TAFs). TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation (1). TAF9 is one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16 (2).

Klemm RD, Goodrich JA, Zhou S, et al. Molecular cloning and expression of the 32-kDa subunit of human TFIID reveals interactions with VP16 and TFIIB that mediate transcriptional activation. Proc. Natl. Acad. Sci. USA 1995; 92:5788-92.

Immunohistochemistry of TAF9 in mouse liver tissue with TAF9 antibody at 5 μ g/mL.