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CD3 Antibody [Hit3a]

CD3 Antibody [Hit3a]

€322.00

Excl. VAT

Item no.	PRS-76-213-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies
Type	Antibody Monoclonal
Format	liquid
Applications	FC, IP, IHC
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	T3E, TCRE, IMD18, CD3E
Available
Shipping	blue ice or RT
By Research Area	Immunology, Functional Assays
Specificity	The Hit3a monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex.
Purification	The monoclonal antibody was purified utilizing affinity chromatography.
Clonality	Monoclonal
Clone	Hit3a
Isotype	Mouse IgG2a, kappa
Conjugate	Unconjugated
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration	batch dependent
Storage Conditions	The product should be stored undiluted at 4˚ C . Do not freeze.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CD3E
Ncbi Gene Id #	916
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CD3E
Ncbi Official Full Name	CD3e molecule, epsilon (CD3-TCR complex)
Ncbi Organism	Homo sapiens
Swissprot #	P07766
Background	The Hit3a monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The HIT3a antibody cross-links with the TCR complex, initiating the cellular activation and proliferation, but it cannot be used for intracellular CD3 staining, as it is able to stain only the surface CD3 complex.
Background References 1	McMichael, A. J. (1987). Leucocyte typing III.Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)
Background References 2	Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background References 3	Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York
Background References 4	Lanier, L. L., Allison, J. P., Phillips, J. H. (1986). Correlation of cell surface antigen expression on human thymocytes by multi-color flow cytometric analysis: implications for differentiation.The Journal of Immunology, 137(8), 2501-2507.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

Listprice: €322.00

Price: €322.00

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Delivery expected until 10/2/2025

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