CYP1A1 Antibody

blue ice or RT

Predicted species reactivity based on immunogen sequence: Monkey

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Rabbit Ig

Supplied in PBS with 0.09% (W/V) sodium azide.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

None

P04798

1543

CYP1A1

Homo sapiens

CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 gene has been associated with lung cancer risk.

Western blot analysis of anti-CYP1A1 Antibody in K562 cell line lysates (35ug/lane).

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP1A1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.