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ICOS Antibody

ICOS Antibody

€645.00

Excl. VAT

Item no.	PRS-62-139-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD278, ICOS, AILIM
Available
Shipping	blue ice or RT
By Research Area	Immunology
Immunogen	This ICOS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human ICOS.
Applications	For IHC-P starting dilution is: 1:50~100 For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Predicted Molecular Weight	23 kDa
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ICOS
Accession #	Q9Y6W8
Protein Gi #	50400701
Ncbi Gene Id #	29851
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	ICOS
Ncbi Official Full Name	Inducible T-cell costimulator
Ncbi Organism	Homo sapiens
Swissprot #	Q9Y6W8
Background	ICOS belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
Background References 1	Okamoto, N., et al., Biochem. Biophys. Res. Commun. 310(3):691-702 (2003).
Background References 2	Okamoto, T., et al., J. Rheumatol. 30(6):1157-1163 (2003).
Background References 3	Riley, J.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(18):11790-11795 (2002).
Background References 4	Haimila, K.E., et al., Immunogenetics 53(12):1028-1032 (2002).
1st Image Caption	Formalin-fixed and paraffin-embedded human lymph with ICOS Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
2nd Image Caption	Western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ICOS antibody detected the ICOS protein (arrow).
3rd Image Caption	Flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

Listprice: €645.00

Price: €645.00

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Delivery expected until 10/2/2025

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