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HtrA1 Antibody

HtrA1 Antibody

€645.00

Excl. VAT

Item no.	PRS-56-986-200ul
Manufacturer	ProSci
Amount	200 ul
Category	Neuroscience Neuroinflammation Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Aging & Neurological Disorders Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine protease HTRA1, 3421-, High-temperature requirement A serine peptidase 1, L56, Serine protease 11, HTRA1, HTRA, PRSS11
Available
Shipping	blue ice or RT
By Research Area	Signal Transduction
Immunogen	This HtrA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-147 amino acids from the N-terminal region of human HtrA1.
Applications	For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50
Predicted Molecular Weight	51 kDa
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	HTRA1
Accession #	Q92743
Protein Gi #	18202620
Ncbi Gene Id #	5654
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	HTRA1
Ncbi Official Full Name	Serine protease HTRA1
Ncbi Organism	Homo sapiens
Swissprot #	Q92743
Background	HtrA1 a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.
Background References 1	Howes, N., et al., Clin Gastroenterol Hepatol 2(3):252-261 (2004).
Background References 2	Chien, J., et al., Oncogene 23(8):1636-1644 (2004).
Background References 3	Hu, S.I., et al., J. Biol. Chem. 273(51):34406-34412 (1998).
Background References 4	Zumbrunn, J., et al., Genomics 45(2):461-462 (1997).
1st Image Caption	Western Blot at 1:2000 dilution + mouse brain lysate Lysates/proteins at 20 ug per lane.
2nd Image Caption	HtrA1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3rd Image Caption	Confocal immunofluorescent analysis of HtrA1 Antibody with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ul

Listprice: €645.00

Price: €645.00

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Delivery expected until 8/7/2025

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