« Back
Home /
Vimentin Antibody

Vimentin Antibody

€645.00

Excl. VAT

Item no.	PRS-50-264-0.1mL
Manufacturer	ProSci
Amount	0.1 mL
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Development Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot Primary Antibodies Intermediate filaments By Organ Testicular & Prostate Cancer Microglia Markers Stem Cell Markers
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Chicken
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Shipping	blue ice or RT
By Research Area	Stem Cell , Cancer
Immunogen	Recombinant human Vimentin purified from E. coli.
Specificity	Specific for the ~50kDa Vimentin protein.
Predicted Molecular Weight	50
Purification	Total IgY fraction
Clonality	Polyclonal
Conjugate	Unconjugated
Storage Conditions	Vimentin antibody can be stored at -20˚ C and is stable at -20˚ C for at least 1 year.
Disclaimer	This product is for research use only.
Modifications	None
Ncbi Official Symbol	VIM
Accession #	P08670
Protein Gi #	55977767
Ncbi Gene Id #	7431
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	VIM
Ncbi Official Full Name	vimentin
Ncbi Organism	Homo sapiens
Swissprot #	P08670
Background	Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).
Background References 1	Nieminen M, Henttinen T, Merinen M, Marttila-Ichihara F, Eriksson JE, Jalkanen S (2006)Vimentin function in lymphocyte adhesion and transcellular migration. Nat Cell Biol8(2):156-62.
Background References 2	Zhao Y, Yan Q, Long X, Chen X, Wang Y (2008) Vimentin affects the mobility and invasiveness of prostate cancer cells. Cell Biochem Funct. May 8
1st Image Caption	Western blot of NIH 3T3 cells showing specific immunolabeling of the ~50k Vimentin protein. Below: Mixed neuron/glial cultures stained with anti-Vimentin (green) and rabbit anti-GFAP antibody (red). Vimentin is expressed alone in fibroblastic and endothelial cells, which are the flattened cells in the middle of the image which appear green. Astrocytes may express primarily GFAP, or GFAP and vimentin, and so appear red (GFAP only) or golden yellow (GFAP and Vimentin). In cells which express both GFAP and vimentin, the two proteins assemble to produce heteropolymer filaments.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mL

Listprice: €645.00

Price: €645.00

available

Delivery expected until 9/4/2025

Quantity:

Compare