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ER Antibody [ER506]

ER Antibody [ER506]

€788.00

Excl. VAT

Item no.	PRS-33-127-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Sarcoma Adenocarcinoma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IHC
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ESR1 Antibody: ER, ESR, Era, ESRA, ESTRR, NR3A1, Estrogen receptor, ER-alpha, ER
Available
Shipping	blue ice or RT
By Research Area	Signal Transduction
Immunogen	Recombinant human ER alpha protein (aa 2-185) was used as the immunogen.
Applications	Western blot: 0.5-1 ug/ml Flow Cytometry: 0.5-1 ug/million cells IHC (Formalin-paraffin): 1-2 ug/ml (1) Variations in protocols, secondaries and substrates may require the ER antibody to be titered for optimal performance. 1. FFPE testing requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min and cooling at RT for 20 minutes.
Purification	Protein G affinity chromatography
Clonality	Monoclonal
Clone	ER506
Isotype	IgG1, kappa
Conjugate	Unconjugated
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration	0.2 mg/mL
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ESR1
Ncbi Gene Id #	2099
User Note	Optimal dilutions for each application to be determined by the researcher
Ncbi Official Symbol	ESR1
Ncbi Official Full Name	estrogen receptor 1
Ncbi Organism	homo sapiens
Swissprot #	P03372
Background	Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. ER presence in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. Clone ER506 antibody strongly stains nuclei of epithelial cells in breast carcinomas.
1st Image Caption	IHC testing of human breast invasive ductal carcinoma with ER antibody (ER506).
2nd Image Caption	Intracellular FACS staining of MCF-7 cells using ER antibody (red) and isotype control (green).
3rd Image Caption	FACS testing of human MCF-7: Black=cells alone; Green=isotype control; Red= Estrogen Receptor PE conjugate
4th Image Caption	Western blot testing of MCF-7 cell lysate with ER antibody (clone ER506). Predicted molecular weight of ER alpha: ~66kDa.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

Listprice: €788.00

Price: €788.00

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Delivery expected until 10/2/2025

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