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Estrogen Receptor beta Antibody

Estrogen Receptor beta Antibody

€451.00

Excl. VAT

Item no.	PRS-18-700-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ESR2, Erb, ESRB, ESTRB, NR3A2, ER-BETA, ESR-BETA
Available
Shipping	blue ice or RT
By Research Area	Cancer, Neuroscience, Obesity, Signal Transduction, Transcription
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Estrogen Receptor beta (NP_001201832.1).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Positive Control 1	MCF-7
Positive Control 2	HeLa
Positive Control 3	Mouse ovary
Positive Control 4	Rat ovary
Positive Control 5	Rat kidney
Predicted Molecular Weight	Observed: 60kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ESR2
Ncbi Gene Id #	2100
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	ESR2
Ncbi Official Full Name	estrogen receptor 2 (ER beta)
Ncbi Organism	Homo sapiens
Swissprot #	Q92731
Background	This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
1st Image Caption	Western blot analysis of extracts of various cell lines, using Estrogen Receptor beta antibody (18-700) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded mouse lung using Estrogen Receptor beta antibody (18-700) at dilution of 1:200 (40x lens).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

Listprice: €451.00

Price: €451.00

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Delivery expected until 10/2/2025

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