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CXCR1 Antibody

CXCR1 Antibody

€451.00

Excl. VAT

Item no.	PRS-16-582-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IL8RA, interleukin 8 receptor, alpha, interleukin 8 receptor alpha, IL8RBA, IL8R1, IL-8 receptor type 1, CXCR1, CMKAR1, CKR-1, chemokine (C-X-C motif) receptor 1, CDw128a, CD181, CD128, C-C-CKR-1, C-C, IL8RA
Available
Shipping	blue ice or RT
By Research Area	Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1 (NP_000625.1).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Positive Control 1	Rat lung
Positive Control 2	Rat spleen
Predicted Molecular Weight	Observed: 70kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CXCR1
Ncbi Gene Id #	3577
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CXCR1
Ncbi Official Full Name	chemokine (C-X-C motif) receptor 1
Ncbi Organism	Homo sapiens
Swissprot #	P25024
Background	The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
1st Image Caption	Western blot analysis of extracts of various cell lines, using CXCR1 antibody (16-582) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded rat lung using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded human colon using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).
4th Image Caption	Immunohistochemistry of paraffin-embedded mouse spleen using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

Listprice: €451.00

Price: €451.00

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Delivery expected until 9/4/2025

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