SARS-CoV-2 Nucleocapsid Antibody, monoclonal

Infectious Disease, COVID-19, Antibody Pairs

This antibody can be paired with other Anti-SARS-CoV-2 Nucleocapsid antibodies to detect SARS-CoV-2 Nucleocapsid protein in sandwich ELISA or LFA assay.

>95% as determined by SDS-PAGE.

Human IgG1/kappa

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization.

For long term storage, the product should be stored at lyophilized state at -20˚ C or lower..Please avoid repeated freeze-thaw cycles.This product is stable after storage at:.-20 to -70˚ C for 12 months in lyophilized state from date of receipt; .-70˚ C for 3 months under sterile conditions after reconstitution.

None

1489678

N

Severe acute respiratory syndrome coronavirus 2

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Immobilized SARS-CoV-2 Nucleocapsid protein, His Tag at 2 ug/mL (100 uL/well) can bind Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 with a linear range of 0.08-1 ng/mL (QC tested).