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Utomilumab Biosimilar - Research Grade

Utomilumab Biosimilar - Research Grade

€3,755.00

Excl. VAT

Item no.	ICH5014-50MG
Manufacturer	IchorBio
Amount	50mg
Category	Antibodies In Vivo Antibodies
Type	Biosimilars
Applications	FA
Specific against	Human (Homo sapiens)
Isotype	IgG1 Lambda
Purity	>95% by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137
Available
Specificity	Detects human CD137. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Utomilumab. This product is for research use only.
Manufacturers Product Category	Low endotoxin, biosimilar antibody
Target Information	4-1BB
Isotype Information	Human IgG2-Lambda 2
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background	RUO Utomilumab is a fully-human IgG2 agonist mAb that selectively binds human 4-1BB/CD137, resulting in NF-κB activation and downstream cytokine production in cell lines and primary lymphocytes. Utomilumab can induce human leukocyte proliferation and has demonstrated significant antitumor activity as a single agent in human peripheral blood lymphocyte (PBL) SCID xenograft tumor models.
Concentration	5mg/ml
Formulation	Sterile, preservative-free, solution in PBS. BSA and Azide free.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Storage	This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Application Notes	This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

Listprice: €3,755.00

Price: €3,755.00

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Delivery expected until 10/2/2025

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