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Antibodies

Anti-Mouse CD70 In Vivo Antibody – Low Endotoxin (TAN 1-7) [ICH1169] European Partner

Item no. ICH1169-5MG
Manufacturer IchorBio
Amount 5mg
Category
Type Antibody
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CD27 Ligand, TNFSF7, Tumor Necrosis Factor Ligand 8A, CD27L, CD70 Antigen
Available
Specificity Clone TAN 1-7 recognizes mouse CD70.
Manufacturers Product Category
Ultra-Low Endotoxin, anti-mouse
Isotype Information
Rat IgG2a Kappa
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution
CD70 is expressed on activated T Cells, B Cells, and dendritic cells.
Background
CD70, a cytokine and also known as CD27 ligand, is a member of the tumor necrosis family. As a cytokine, CD70 plays a role in regulating B cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. Non-small cell lung cancer research has shown that CD70 increases the survivability of tumor cells and T cells by signaling through its receptor CD27.
Immunogen
Recombinant mouse CD70 (extracellular domain, aa residues 41-195).
Concentration
>2.0 mg/ml
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Aggregation
Aggregation level ≤ 5%
Storage
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5mg
Available: In stock
available

Delivery expected until 8/7/2025 

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