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Antibodies

Anti-Mouse DNGR-1 In Vivo Antibody – Ultra Low Endotoxin (1F6) [ICH1168] European Partner

€556.00
Excl. VAT
Item no. ICH1168UL-5MG
Manufacturer IchorBio
Amount 5mg
Category
Type Antibody
Applications WB, FC
Clone 1F6
Specific against Mouse (Murine, Mus musculus)
Host Rat
Isotype IgG1
Purity >98% by SDS-PAGE and HPLC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CD370, DNGR-1, C-Type Lectin Domain Family 9 Member A
Available
Specificity Clone 1F6 recognizes an epitope on mouse DNGR1
Manufacturers Product Category
Ultra-Low Endotoxin, anti-mouse
Target Information
CLEC9A
Isotype Information
Rat IgG1
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution
CD370 (CLEC9A) in mice is expressed on CD8+ DCs and at low levels by plasmacytoid DCs.
Background
CLEC9A, also known as DNGR1 is defined as a type II membrane protein with a single extracellular C-type lectin domain¹. CLEC9A is involved with adaptive immune response during infection. Additionally, CLEC9A, is being investigated for potential to enhance immune responses produced by vaccines.
Immunogen
RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope.
Concentration
>2.0 mg/ml
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Aggregation
Aggregation level ≤ 1%
IMPACT Pathogen Test
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: - Mycoplasma spp. - Mycoplasma pulmonis - Sendai virus - Mouse hepatitis virus - Pneumonia virus of mice - Minute virus of mice - Mouse parvovirus (MPV1-5) - Theiler’s murine encephalomyelitis virus - Murine norovirus - Reovirus 3 - Mouse rotavirus - Ectromelia virus - Lymphocytic choriomeningitis virus - Polyoma virus - Lactate dehydrogenase-elevating virus - Mouse adenovirus (MAD1, MAD2) - Mouse cytomegalovirus - K virus - Mouse thymic virus - Hantaan virus - Corynebacterium bovis - Corynebacterium spp. (HAC2)
Storage
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5mg
Available: In stock
Listprice: €556.00
Price: €556.00
available

Delivery expected until 9/18/2025 

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