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Anti-Mouse NK1.1 In Vivo Antibody - Low Endotoxin (PK136)

Anti-Mouse NK1.1 In Vivo Antibody - Low Endotoxin (PK136)

Item no.	ICH1128-25MG
Manufacturer	IchorBio
Amount	25mg
Category	Antibodies In Vivo Antibodies Western Blot Blocking
Type	Antibody
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Natural Killer Cells, KR-P1C, NKR-P1B, Ly-55, CD161b, CD161c
Available
Specificity	Anti-NK1.1 In Vivo Antibody - Low Endotoxin (PK136) recognizes an epitope on Mouse NK1.1
Manufacturers Product Category	Low Endotoxin, anti-mouse
Target Information	NK1.1
Isotype Information	Mouse IgG2a Kappa
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	Mouse NK cells. Endogenous and interferon induced NK cells. Not present on cytotoxic T-cells and Con A stimulated blast cells. May be present on a certain subset of cytotoxic T-cells strains A, AKR, BALB/C, BALB.H-2b, CBA, C3H, DBA/2, 124 were negative using PK136.
Background	NK-1.1 surface antigen, also known as CD161b/CD161c, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
Immunogen	NK-1+ cells from mouse spleen and bone marrow
Concentration	1.0 - 5.0 mg/ml
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 5%
Storage	anti-NK1.1 In Vivo Antibody - Low Endotoxin (PK136) is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 8/7/2025

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