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Anti-Mouse ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1)

Anti-Mouse ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1)

Item no.	ICH1101-50MG
Manufacturer	IchorBio
Amount	50mg
Category	Oncology Neuroscience Neural Lineage Markers Antibodies In Vivo Antibodies By Cell Type Hematology Myeloma Cell Biology Cell Movement Cell Adhesion Western Blot Blocking
Type	Antibody
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54
Available
Specificity	Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) recognizes the (Mr 95 kD) cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18).
Manufacturers Product Category	Low Endotoxin, anti-mouse
Target Information	ICAM-1
Isotype Information	Rat IgG2a
Antigen Distribution	The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Background	Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies
Immunogen	Purified Recombinant Mouse ICAM-1 (>98%)
Concentration	0.5 mg/ml
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 5%
Storage	anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes	Blocking: This antibody blocks the binding LFA-1 (CD11a/CD18) to ICAM-1. The antibody is suitable for studies of inflammation, lymphocyte differentiation, and lymphocyte activation. - Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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Delivery expected until 8/7/2025

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