GPER1 Antibody

G protein-coupled estrogen receptor 1

Q99527

ELISA, WB, IHC, ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

WB:1:200-1:1000

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3, 4, 5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Antigen affinity purification

Epigenetics and Nuclear Signaling?Neuroscience, Metabolism, Signal transduction