Comparison

SIGIRR Antibody

€173.00
Excl. VAT
Item no. CSB-PA743558ESR1HU-50ul
Manufacturer Cusabio
Amount 50ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8), SIGIRR
Similar products SIGIRR, Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8)
Available
Aliases
Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8), SIGIRR
Immunogen Species
Human
UniprotID
Q6IA17
Immunogen
Recombinant Human Single Ig IL-1-related receptor protein (1-120AA)
Applications info
ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Dilution ratio 1
ELISA:1:2000-1:10000
Dilution ratio 2
WB:1:1000-1:5000
Dilution ratio 3
IHC:1:20-1:200
Background
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Stroage
Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method
Antigen Affinity Purified
Target Names
SIGIRR
General Research Areas
Immunology, Signal transduction
Initial Research Areas
Immunology

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50ul
Available: In stock
Listprice: €173.00
Price: €173.00
available

Delivery expected until 9/11/2025 

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