Anti-SYP/Synaptophysin Antibody Picoband™ (monoclonal, 3G12)

Boster Bio Anti-SYP/Synaptophysin Antibody Picoband™ (monoclonal, 3G12) catalog # M05049-3. Tested in WB applications. This antibody reacts with Mouse, Rat.

SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present inneuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

Western blot, 0.1-0.5μg/ml, Mouse, Rat

Monoclonal

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

synaptophysin

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).

Synaptophysin