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Phospho-c-Myc-S62 Rabbit mAb

Phospho-c-Myc-S62 Rabbit mAb

€3,520.00

Excl. VAT

Item no.	AP0989-1000uL
Manufacturer	Abclonal
Amount	1000 uL
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	Affinity purification
Sequence	PLSPS
NCBI	MYC
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	MRTL, MYCC, bHLHe39, c-Myc
Available
Background	This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
Route	Synthetic Peptide
Manufacturers Category	Phosphorylated Antibodies
Immunogen	A synthetic phosphorylated peptide around S62 of human c-Myc (NP_002458.2).
Storage	Store at -20℃. Avoid freeze / thaw cycles.\|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilution	WB, 1:500 - 1:1000
Protein Size	51kDa
Manufacturers Research Area	Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Cancer, Tumor biomarkers, Signal Transduction, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Cell differentiation, Cell Cycle Control-G1 S Checkpoint, Endocrine Metabolism, Warburg Effect, Immunology Inflammation, Jak-Stat-IL-6 Receptor Signaling Pathway, Stem Cells
Gene Symbol	MYC

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1000 uL

Listprice: €3,520.00

Price: €3,520.00

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Delivery expected until 9/30/2025

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