SARS-CoV-2/COVID-19 Spike Glycoprotein RBD Nanobody

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Glycoprotein Receptor-Binding Domain Protein Nanobody is a recombinant monoclonal antibody expressed in HEK293 cells for the detection of SARS-CoV-2/COVID-19 S RBD Protein. This antibody contains V_HH fused with Human IgG1 Fc at the C-terminus.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

Recombinant

Purified by affinity chromatography.

P0DTC2

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.

This product is for research use only.