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VISTA Antibody [8E11]

VISTA Antibody [8E11]

Item no.	ABC-ASC12162
Manufacturer	Abcepta
Amount	0.1 mg
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	IF, ICC, ELISA, IHC-P
Clone	VSIR
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	C10orf54, GI24, PP2135, SISP1, B7-H5, VISTA, B7H5, DD1alpha, PD-1H, V-set immunoregulatory receptor, VSIR, VISTA Antibody: VISTA molecule, chromosome 10 open reading frame 54, V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation, Chromosome 10 Open Reading Frame 54
Available
Primary Accession	Q9H7M9
Application	IHC-P, IF, ICC, E
Bio Background	VISTA Antibody: VISTA/B7-H5/platelet receptor Gi24 is a single-pass type I membrane protein located at the cell surface. It is an immunoregulatory receptor which can inhibit T-cell response and may promote differentiation of embryonic stem cells, by inhibiting the BMP4 signaling pathway. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation.
Bio References	Mayya V., et al . Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. 2009, Sci. Signal. 2:RA46-RA46.Sakr M.A., et al., GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase. 2010, Cancer Sci. 101:2368-2374.
Clonality	Monoclonal
Gene ID	64115
Gene Name	VSIR (HGNC:30085)
Other Accession	NP_071436
Isotype	IgG1
Calculated MW	33908
	Clone: VSIR
Purification	VISTA Antibody is supplied as protein A purified IgG1.
Reconstitution & Storage	VISTA antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control	Cat. No. 1331 - Human Lymphoma Tissue Lysate; Cat. No. 1306 - Human Spleen Tissue;
Buffer	VISTA Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 10/2/2025

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