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CD70 Antibody (Center)

CD70 Antibody (Center)

€207.00

Excl. VAT

Item no.	ABC-AP14744c-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CD70, CD27L, CD27LG, TNFSF7, CD70 antigen, CD27 ligand, Tumor necrosis factor ligand superfamily member 7, CD27-L
Available
Primary Accession	P32970
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Bio References	Arimoto-Miyamoto, K., et al. Immunology 130(1):137-149(2010) Shaw, J., et al. Blood 115(15):3051-3057(2010) Yu, S.E., et al. Mol. Cells 29(2):217-221(2010) Kozlowska, A., et al. J. Rheumatol. 37(1):53-59(2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Clonality	Polyclonal
Clone/Animal Names	RB34943
Gene ID	970
Gene Name	CD70
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	CD70 Antibody (Center) (Cat. #AP14744c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD70 antibody detected the CD70 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	CD70 Antibody (Center) (AP14744c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD70 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_001243.1
Isotype	Rabbit Ig
Calculated MW	21118
Antigen Region	72-101
Antigen Source	HUMAN
Target/Specificity	This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.
NCBI Accession	NP_001243.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

Listprice: €207.00

Price: €207.00

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Delivery expected until 10/2/2025

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