Mouse Monoclonal Antibody to TIM3

Catalog Number: sAP-1705
Product Name: Mouse Monoclonal Antibody to TIM3
Target Molecle: TIM3
Aliases: HAVCR2; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2
Species: Human;
MW: 33.4kDa
Enterez GeneID: 84868
General Information: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Immunogen: Purified recombinant fragment of human TIM3 (AA: extra 22-202) expressed in HEK293 cells.
Clone: MM7C8A7
Isotype: Mouse IgG1
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; ICC: 1 to 200 - 1 to 1000; FCM: 1 to 200 - 1 to 400; IHC: N to A
References: 1.Clin Exp Immunol. 2016 Mar; 183(3):419-30.2.J Leukoc Biol. 2010 Nov; 88(5):905-12.