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Caspase 3 (Apopain) Substrate 1m, fluorogenic

Caspase 3 (Apopain) Substrate 1m, fluorogenic

€296.00

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Item no.	AS-25262-5
Manufacturer	AnaSpec
Amount	5 mg
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Cell Biology Cell Status Apoptosis Reagents & Chemicals Staining & Dyes Fluorescent Reagents
Type	Fluorescent dyes and probes
Specific against	other
Sequence	Ac-Asp-Glu-Val-Asp-AMC
Citations	Koeplinger KA, et al. (2000). Caspase 8: an efficient method for large-scale autoactivation of recombinant procaspase 8 by matrix adsorption and characterization of the active enzyme. Protein Expr Purif 18, 378-87; Garcia-Calvo M, et al. (1998). Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem 273, 32608-13; Thornberry NA, et al. (1997). A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem 272, 17907-11; Rano TA, et al. (1997). A combinatorial approach for determining protease specificities: application to interleukin-1 beta converting enzyme (ICE). Chem Biol 4, 149-55; Margolin N, et al. (1997). Substrate and inhibitor specificity of interleukin-1 ?-converting enzyme and related caspases. J Biol Chem 272, 7223-8; Mizushima N, et al. (1996). Ceramide induces apoptosis via CPP32 activation. FEBS Lett 395, 267-71; Faubion WA, et al. (1999). Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Invest 103, 137-45.
ECLASS 10.1	30196090
ECLASS 11.0	30196090
UNSPSC	12000000
Alias	Ac-DEVD-AMC
Available
Description	AMC (7-amino-4-methylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AMC peptides by caspases generates strongly fluorescent AMC that is monitored fluorimetrically at 440-460 nm with excitation of 340-350 nm.
MW	675, 5
One-Letter Code	Ac-DEVD-AMC
Product Group	LB1A3Z
Research Topic	Apoptosis
Research Topic 2	Cancer Research
Shipping	RT
Storage	-20C desiccated and protected from light

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

Listprice: €296.00

Price: €296.00

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Delivery expected until 9/11/2025

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