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Alpha-2-macroglobulin

Alpha-2-macroglobulin

€229.00

Excl. VAT

Item no.	ARP-13-3010
Manufacturer	American Research Products
Amount	100 ug
Category	Peptides & Proteins Native Proteins
Type	Proteins Native
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	A major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. Multifunctional, it promotes growth of mammalian cells in culture, stimulates the regeneration of lymphocytes in irradiated mice, possesses a transport function for zinc and is a proteinase inhibitor that controls the clotting and fibrinolytic system. Clinically levels are increased in liver cirrhosis, nephrotic syndrome, diabetes, and severe burn cases.
Background	Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Form	Purified protein, in 30 mM Na Phosphate, pH 7.0 , with glycine as a stabilize and 0.1% sodium azide.
Storage	2-8C for immediate use, or at -20C (aliquot)
Synonyms	A2M, A2MD, CPAMD5, FWP007, S863-7
Purity	Greater than 95% determined by SDS-PAGE. Cellulose acetate electrophoresis shows the major product to have alpha-2 mobility. Protein determination by the method of Lowry and Polyacrylamide gradient gel electrophoresis shows one band only corresponding the molecular weight of Alpha-2-macroglobulin.
Source	Human plasma. Blood sample from donors was tested and found negative for HBsAg, HIV-1&, 2 antibodies, HCV and Syphilis
Notes	Because no test method can offer complete assurance that products derived from human source will not transmit infectious agents, it is recommended that this product be handled with the same precautions used for patient specimens.
Molecular Weight	725000

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

Listprice: €229.00

Price: €229.00

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Delivery expected until 9/18/2025

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