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VPS34-IN1

VPS34-IN1

Item no.	M5344-50mg
Manufacturer	AbMole
Amount	50mg
Category	Oncology By Cell Type Cell Biology Cell Status Autophagy Cardiovascular Research Myocardial Infarction Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Cas #	1383716-33-3
Bioactivity information	Administration of VPS34-IN1 to cells induces a rapid dose-dependent dispersal of a specific PtdIns(3)P-binding probe from endosome membranes, within 1min, without affecting the ability of class I PI3K to regulate Akt. It can also induce a rapid ca.50-60% loss of SGK3 phosphorylation within 1min. VPS34-IN1 has no inhibition to the SGK2 isoform that does not possess a PtdIns(3)P-binding PX domain.
Target	PI3K
Synonyms	Vps34-IN-1
MW	425, 91
Formula	C21H24ClN7O
Solubility	85 mg/mL in DMSO
Purity	>98%

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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M5344-50mg-safety-datasheet.pdf