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Vincristine sulfate

Vincristine sulfate

€40.00

Excl. VAT

Item no.	M1892-10mg
Manufacturer	AbMole
Amount	10mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Lymphatic System Cancer
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Cas #	2068-78-2
Bioactivity information	Vincristine (leurocristine, Oncovin), sometimes abbreviated "VCR", is a kind of microtubule function inhibitor. Vincristine sulfate is the salt of an alkaloid from the flowering periwinkle plant (also known as Vinca rosea Linn). Vincristine sulfate induces apoptosis in human lymphoma cells. Vincristine binds to tubulin dimers, inhibiting assembly of microtubule structures. The IC50 and IC90 of vincristine for the 4 vaccine-associated feline sarcoma (VAFS) cell lines were between 0.005 to 0.039 ug/ml and 0.045 to 1.027 ug/ml, respectively.
Target	Microtubule
Synonyms	leurocristine, Oncovin
MW	923, 04
Formula	C46H56N4O10.H2SO4
Solubility	DMSO 150 mg/mL, Water 150 mg/mL
Purity	1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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M1892-10mg-safety-datasheet.pdf