22-Oxa-9,25-dihydroxyvitamin D3

C26H42O4

Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals

22-Oxa-9, 25-dihydroxyvitamin D3 is an analogue of Vitamin D3 (V676045), which mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. Occurs in and is isolated from fish liver oils. Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.

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