FITC Anti-Human HLA-DR (L243)

The L243 antibody reacts with a member of the human MHC Class II antigens, HLA-DR. The HLA-DR antigen is expressed on B lymphocytes, activated T lymphocytes, activated NK cells, monocytes, macrophages, other antigen presenting cells and progenitor cells. The L243 antibody is specific to an epitope on the alpha subunit of the heterodimeric HLA-DR protein and binds a different epitope than the LN3 antibody clone. It does not cross-react with HLA-DP or HLA-DQ. This antibody is reported to be cross-reactive with non-human primates including Chimpanzee, Cynomolgus, Rhesus and Baboon. Please choose the appropriate format for each application.

Brodsky FM. 1984. Immunogenetics. 19(3): 179-194.

Robbins PA, Evans EL, Ding AH, Warner NL and Brodsky FM. 1987. Human Immunol. 18(4): 301-313.

Poulin LF, Reyal Y, Uronen-Hansson H, Schraml BU, Sancho D, Murphy KM, Hakansson UK, Moita LF, Agace WW, Bonnet D and Reis e Sousa C. 2012. Blood. 119(25): 6052-6062. (Flow cytometry)

Shio MT, Hassan GS, Shah WA, Nadiri A, El Fakhry Y, Li H and Mourad W. 2014. J Immunol. 192(6): 2543-2550. (Flow cytometry)

Bigley V, McGovern N, Milne P, Dickinson R, Pagan S, Cookson S, Haniffa M and Collin M. 2015. J Leukoc Biol. 97(4): 627-634. (Flow cytometry)

Goodier MR and Londei M. 2000. J Immunol. 165(1): 139-147. (Depletion)

Kalka-Moll WM, Tzianabos AO, Bryant PW, Niemeyer M, Ploegh HL and Kasper DL. 2002. J Immunol. 169(11): 6149-6153. (Blocking)