Anti-PRDM2 antibody

203,00 €

Zzgl. MwSt.

ArtNr	STJ111300-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Oncology Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Head & Neck Cancer
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Pr Domain Zinc Finger Protein 2 antibody</br>Anti-Gata-3-Binding Protein G3b antibody</br>Anti-Lysine N-Methyltransferase 8 antibody</br>Anti-Mtb-Zf antibody</br>Anti-Mte-Binding Protein antibody</br>Anti-Pr Domain-Containing Protein 2 antibody</br>A
Similar products	Anti-Pr Domain Zinc Finger Protein 2 antibody Anti-Gata-3-Binding Protein G3b antibody Anti-Lysine N-Methyltransferase 8 antibody Anti-Mtb-Zf antibody Anti-Mte-Binding Protein antibody Anti-Pr Domain-Containing Protein 2 antibody A
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q13029
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID	7799
Gene symbol	PRDM2
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PRDM2 (NP_036363. 2).
Short Description	Rabbit polyclonal against PRDM2
Tissue specificity	Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3.
Cellular localization	Nucleus
Molecular weight	Calculated: 25kDa/162kDa/166kDa/184kDa/188kDa. Observed: 250kDa
Dilution range	WB 1:500-1:2000 IHC 1:50-1:200
Alternative names	Anti-Pr Domain Zinc Finger Protein 2 antibody Anti-Gata-3-Binding Protein G3b antibody Anti-Lysine N-Methyltransferase 8 antibody Anti-Mtb-Zf antibody Anti-Mte-Binding Protein antibody Anti-Pr Domain-Containing Protein 2 antibody Anti-Retinoblastoma Protein-Interacting Zinc Finger Protein antibody Anti-Zinc Finger Protein Riz antibody Anti-PRDM2 KMT8 RIZ antibody
Protein name	Pr Domain Zinc Finger Protein 2 Gata-3-Binding Protein G3b Lysine N-Methyltransferase 8 Mtb-Zf Mte-Binding Protein Pr Domain-Containing Protein 2 Retinoblastoma Protein-Interacting Zinc Finger Protein Zinc Finger Protein Riz
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	PRDM2_HUMAN

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Menge: 50ul

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Preis: 203,00 €

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