Anti-AIF antibody

Unconjugated

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Store at-20° C, and avoid repeat freeze-thaw cycles.

Mouse monoclonal to AIF.

AIFM1

Mouse monoclonal against AIF

Mitochondrion intermembrane space. Mitochondrion inner membrane. Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Proteolytic cleavage during or just after translocation into the mitochondrial intermembrane space (IMS) results in the formation of an inner-membrane-anchored mature form (AIFmit). During apoptosis, further proteolytic processing leads to a mature form, which is confined to the mitochondrial IMS in a soluble form (AIFsol). AIFsol is released to the cytoplasm in response to specific death signals, and translocated to the nucleus, where it induces nuclear apoptosis. Colocalizes with EIF3G in the nucleus and perinuclear region.. Isoform 3: Mitochondrion intermembrane space Mitochondrion inner membrane. Has a stronger membrane anchorage than isoform 1.. Isoform 5: Cytoplasm

WB 1:1000
ICC 1:200

Apoptosis-inducing factor 1, mitochondrial
Programmed cell death protein 8

O95831_HUMAN