Anti-CXCR2 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P25025

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.

CXCR2

Rabbit polyclonal against CXCR2

Calculated: 40kDa. Observed: 43kDa

Anti-C-X-C Chemokine Receptor Type 2 antibody
Anti-Cxc-R2 antibody
Anti-Cxcr-2 antibody
Anti-Cdw128b antibody
Anti-Gro/Mgsa Receptor antibody
Anti-High Affinity Interleukin-8 Receptor B antibody
Anti-Il-8r B antibody
Anti-Il-8 Receptor Type 2 antibody
Anti-Cd Antigen Cd182 antibody
Anti-CXCR2 IL8RB antibody

FOR RESEARCH USE ONLY (RUO).