Anti-PRG2 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P13727

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

PRG2

Rabbit polyclonal against PRG2

Bone Marrow Proteoglycan: Secreted
The Proform Is Secreted
Eosinophil Granule Major Basic Protein: Cytoplasmic Vesicle
Secretory Vesicle
The Mature Protein Is Found In The Matrix Of The Eosinophil's Large Specific Granule (Crystalloid Core)

WB 1:500-1:2000

Bone Marrow Proteoglycan
Bmpg
Proteoglycan 2 Cleaved Into-Eosinophil Granule Major Basic Protein
Embp
Mbp
Pregnancy-Associated Major Basic Protein

PRG2_HUMAN