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Anti-Phospho-RB1-(S780) antibody

217,00 €
Zzgl. MwSt.
ArtNr STJ22373-50
Hersteller St John's Laboratory
Menge 50ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Retinoblastoma-Associated Protein antibody</br>Anti-P105-Rb antibody</br>Anti-P110-Rb1 antibody</br>Anti-Prb antibody</br>Anti-Rb antibody</br>Anti-Pp110 antibody</br>Anti-RB1 antibody
Similar products Anti-Retinoblastoma-Associated Protein antibody
Anti-P105-Rb antibody
Anti-P110-Rb1 antibody
Anti-Prb antibody
Anti-Rb antibody
Anti-Pp110 antibody
Anti-RB1 antibody
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P06400
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Gene ID
Gene symbol
RB1
Immunogen
A phospho specific peptide corresponding to residues surrounding S780 of human RB1
Short Description
Rabbit polyclonal against Phospho-RB1-(S780)
Tissue specificity
Expressed in the retina. Expressed in foreskin keratinocytes (at protein level).
Cellular localization
Nucleus
During Keratinocyte Differentiation
Acetylation By Kat2b/Pcaf Is Required For Nuclear Localization
Molecular weight
Calculated: 106kDa. Observed: 100kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Retinoblastoma-Associated Protein antibody
Anti-P105-Rb antibody
Anti-P110-Rb1 antibody
Anti-Prb antibody
Anti-Rb antibody
Anti-Pp110 antibody
Anti-RB1 antibody
Protein name
Retinoblastoma-Associated Protein
P105-Rb
P110-Rb1
Prb
Rb
Pp110
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
Listenpreis: 217,00 €
Preis: 217,00 €
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Lieferung vsl. bis 28.08.2025 

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