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Anti-S100A8 antibody

277,00 €
Zzgl. MwSt.
ArtNr STJ117510-100
Hersteller St John's Laboratory
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Protein S100-A8 antibody</br>Anti-Calgranulin-A antibody</br>Anti-Calprotectin L1l Subunit antibody</br>Anti-Cystic Fibrosis Antigen antibody</br>Anti-Cfag antibody</br>Anti-Leukocyte L1 Complex Light Chain antibody</br>Anti-Migration Inhibitory Fact
Similar products Anti-Protein S100-A8 antibody
Anti-Calgranulin-A antibody
Anti-Calprotectin L1l Subunit antibody
Anti-Cystic Fibrosis Antigen antibody
Anti-Cfag antibody
Anti-Leukocyte L1 Complex Light Chain antibody
Anti-Migration Inhibitory Fact
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P05109
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human S100A8 (NP_002955. 2).
Short Description
Rabbit polyclonal against S100A8
Tissue specificity
Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers.
Cellular localization
Secreted
Cytoplasm
Cytoskeleton
Cell Membrane
Peripheral Membrane Protein
Predominantly Localized In The Cytoplasm
Upon Elevation Of The Intracellular Calcium Level
Translocated From The Cytoplasm To The Cytoskeleton And The Cell Membrane
Upon Neutrophil Activation Or Endothelial Adhesion Of Monocytes
Is Secreted Via A Microtubule-Mediated
Alternative Pathway
Molecular weight
Calculated: 10kDa. Observed: 11kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Protein S100-A8 antibody
Anti-Calgranulin-A antibody
Anti-Calprotectin L1l Subunit antibody
Anti-Cystic Fibrosis Antigen antibody
Anti-Cfag antibody
Anti-Leukocyte L1 Complex Light Chain antibody
Anti-Migration Inhibitory Factor-Related Protein 8 antibody
Anti-Mrp-8 antibody
Anti-P8 antibody
Anti-S100 Calcium-Binding Protein A8 antibody
Anti-Urinary Stone Protein Band A antibody
Anti-S100A8 CAGA CFAG MRP8 antibody
Protein name
Protein S100-A8
Calgranulin-A
Calprotectin L1l Subunit
Cystic Fibrosis Antigen
Cfag
Leukocyte L1 Complex Light Chain
Migration Inhibitory Factor-Related Protein 8
Mrp-8
P8
S100 Calcium-Binding Protein A8
Urinary Stone Protein Band A
Note
FOR RESEARCH USE ONLY (RUO).
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
Listenpreis: 277,00 €
Preis: 277,00 €
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Lieferung vsl. bis 07.08.2025 

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