Anti-Kv2.1/KCNB1 antibody

Unconjugated

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Store at-20° C, and avoid repeat freeze-thaw cycles.

Rabbit polyclonal to Kv2.1/KCNB1.

KCNB1

Rabbit polyclonal against Kv2.1/KCNB1

Cell Membrane
Perikaryon
Cell Projection
Axon
Dendrite
Membrane
Multi-Pass Membrane Protein
Cell Junction
Synapse
Postsynaptic Cell Membrane
Synaptosome
Lateral Cell Membrane
Sarcolemma
Localizes To High-Density Somatodendritic Clusters And Non-Clustered Sites On The Surface Of Neocortical And Hippocampal Pyramidal Neurons In A Cortical Actin Cytoskeleton-Dependent Manner
Localizes Also To High-Density Clusters In The Axon Initial Segment (Ais)
At Ankyrin-G-Deficient Sites
On The Surface Of Neocortical And Hippocampal Pyramidal Neurons
Kcnb1-Containing Ais Clusters Localize Either In Close Apposition To Smooth Endoplasmic Reticulum Cisternal Organelles Or With Gaba-A Receptor-Containing Synapses Of Hippocampal And Cortical Pyramidal Neurons
Respectively
Localizes To High-Density Clusters On The Cell Surface Of Atrial And Ventricular Myocytes And At The Lateral Plasma Membrane In Epithelial Cells
Localizes Both To The Axial And Transverse Tubules (T Tubule) And Sarcolemma In Ventricular Myocytes
Associated With Lipid Raft Domains
In Cortical Neurons
Apoptotic Injuries Induce De Novo Plasma Membrane Insertion In A Snare-Dependent Manner Causing An Apoptotic Potassium Current Surge

WB 1:500-2000
ELISA 1:10000-20000

Potassium Voltage-Gated Channel Subfamily B Member 1
Delayed Rectifier Potassium Channel 1
Drk1
H-Drk1
Voltage-Gated Potassium Channel Subunit Kv2.1

KCNB1_HUMAN