Anti-AIF-M1 antibody

Polyclonal

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

O95831

1 mg/ml

9131

Synthesized peptide derived from human AIF-M1

Rabbit polyclonal against AIF-M1

Mitochondrion Intermembrane Space
Mitochondrion Inner Membrane
Cytoplasm
Nucleus
Perinuclear Region
Proteolytic Cleavage During Or Just After Translocation Into The Mitochondrial Intermembrane Space (Ims) Results In The Formation Of An Inner-Membrane-Anchored Mature Form (Aifmit)
During Apoptosis
Further Proteolytic Processing Leads To A Mature Form
Which Is Confined To The Mitochondrial Ims In A Soluble Form (Aifsol)
Aifsol Is Released To The Cytoplasm In Response To Specific Death Signals
And Translocated To The Nucleus
Where It Induces Nuclear Apoptosis
Colocalizes With Eif3g In The Nucleus And Perinuclear Region
Isoform 3: Mitochondrion Intermembrane Space
Has A Stronger Membrane Anchorage Than Isoform 1
Isoform 4: Mitochondrion
Cytosol
In Pro-Apoptotic Conditions
Is Released From Mitochondria To Cytosol In A Calpain/Cathepsin-Dependent Manner
Isoform 5: Cytoplasm

WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000

Apoptosis-Inducing Factor 1-Mitochondrial
Programmed Cell Death Protein 8

AIFM1_HUMAN