Anti-EZR antibody

203,00 €

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ArtNr	STJ29814-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies Microglia Markers
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Ezrin antibody</br>Anti-Cytovillin antibody</br>Anti-Villin-2 antibody</br>Anti-P81 antibody</br>Anti-EZR VIL2 antibody
Similar products	Anti-Ezrin antibody Anti-Cytovillin antibody Anti-Villin-2 antibody Anti-P81 antibody Anti-EZR VIL2 antibody
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P15311
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Gene ID	7430
Gene symbol	EZR
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human EZR (NP_003370. 2).
Short Description	Rabbit polyclonal against EZR
Tissue specificity	Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.
Cellular localization	Apical Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cell Projection Microvillus Membrane Ruffle Membrane Cytoplasm Cell Cortex Cytoskeleton Microvillus Localization To The Apical Membrane Of Parietal Cells Depends On The Interaction With Mpp5 Localizes To Cell Extensions And Peripheral Processes Of Astrocytes Microvillar Peripheral Membrane Protein (Cytoplasmic Side)
Molecular weight	Calculated: 69kDa. Observed: 90kDa
Dilution range	WB 1:500-1:2000 IHC 1:50-1:100
Alternative names	Anti-Ezrin antibody Anti-Cytovillin antibody Anti-Villin-2 antibody Anti-P81 antibody Anti-EZR VIL2 antibody
Protein name	Ezrin Cytovillin Villin-2 P81
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	EZRI_HUMAN

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Menge: 50ul

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Preis: 203,00 €

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