Anti-PLAU antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P00749

This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

PLAU

Rabbit polyclonal against PLAU

Secreted

WB 1:500-1:2000

Urokinase-Type Plasminogen Activator
U-Plasminogen Activator
Upa Cleaved Into-Urokinase-Type Plasminogen Activator Long Chain A-Urokinase-Type Plasminogen Activator Short Chain A-Urokinase-Type Plasminogen Activator Chain B

UROK_HUMAN