Anti-ITGAM antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P11215

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

ITGAM

Rabbit polyclonal against ITGAM

Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft

WB 1:500-1:2000

Integrin Alpha-M
Cd11 Antigen-Like Family Member B
Cr-3 Alpha Chain
Cell Surface Glycoprotein Mac-1 Subunit Alpha
Leukocyte Adhesion Receptor Mo1
Neutrophil Adherence Receptor
Cd Antigen Cd11b

ITAM_HUMAN